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Please use this identifier to cite or link to this item: https://elib.bsu.by/handle/123456789/197431
Title: Нарушение прооксидантно-антиоксидантного баланса в печени крыс при эндотоксемии
Authors: Семак, Игорь Викторович
Корик, Елена Олеговна
Канапацкая, Ирина Анатольевна
Наумова, Мария Викторовна
Кульчицкий, Владимир Адамович
Keywords: ЭБ БГУ::ЕСТЕСТВЕННЫЕ И ТОЧНЫЕ НАУКИ::Биология
Issue Date: 2002
Publisher: Минск : БГУ
Citation: Вестник Белорусского государственного университета. Сер. 2, Химия. Биология. География. – 2002. - № 3. – С. 41-46.
Abstract: Functional state of antioxidant system in liver of rats under conditions of modulated septic shock was studied. Depression of intracellular antiperoxide defense as a result of disbalance in the work of enzymes, generating and destroying H2O2 during endotoxemia was found. At the same time activation of microsomal glutathion. S-transferase, superoxide dismutase and redistribution of cytosolic glutathion S-transferases towards izoenzymes, possessing high peroxide activity was found. It is obvious, that in spite of activation of some intracellular protective mechanisms, liver becomes extremely sensitive to oxidative stress.
URI: http://elib.bsu.by/handle/123456789/197431
ISSN: 0372-5340
Appears in Collections:2002, №3 (октябрь)

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